Interdigital webbing The spaces between the toes are known as the interdigital spaces of foot (a. Jan 1, 2018 · Reduction of interdigital cell death, which leads to interdigital web formation, arose recurrently in independent lineages of different taxa. Oct 10, 2006 · Retention of interdigital webbing in the bat would have been an important step to developing true powered flight and likely contributed to the success of this widespread and diverse order. We find that bat forelimb and hindlimb interdigital tissues express Bmp signaling components but that only bat hindlimbs undergo interdigital apoptosis. The webbing can consist of membrane, skin, or other connective tissue and varies widely in different taxa. Another step in the evolution of bat wings was the elongation of the forelimb digits to support the wing membrane. The interdigital webbing and foot pads are examined for discoloration, abrasions, and other conditions. By using a functional assay, we show that maintenance of interdigit tissue in the bat wing depends on the combined effects of high levels of Fgf signaling and inhibition of Bmp Retention of interdigital webbing in the bat would have been an important step to developing true powered flight and likely contributed to the success of this widespread and diverse order. Strikingly, the retention of interdigital webbing in the bat forelimb is correlated with a unique pattern of Fgf8 expression in addition to the Bmp inhibitor Gremlin. Rasweiler IV§, and Lee A. tqfiwpjdljcdfjfbdzvcyuadcmxokwaqrymvlvoednzhdebzdgwophkemv